What is 2-phenylacetamide used for?

Apr 10, 2025 Leave a message

2-phenylacetamide Structure & 2-phenylacetamide formula

The chemical formula of 2-phenylacetamide is C8H9NO.

Its structure consists of a phenyl group (C6H5) attached to an acetamide group (-CH2CONH2). Here's a breakdown of the structure:

Phenyl group (C6H5): A benzene ring (C6H5), which is a six-membered carbon ring with alternating double bonds.

Acetamide group (CH3-CO-NH2): An acetamide group where the carbonyl group (C=O) is bonded to a nitrogen atom (NH2), and the nitrogen is further bonded to a methyl group (CH3).

In 2-phenylacetamide, the phenyl group is attached to the second position of the acetamide group (on the CH2 group), which is why it's referred to as 2-phenylacetamide CAS 103-81-1.

Here's a simple structural representation of 2-phenylacetamide CAS 103-81-1:

Copy Code

H2N-C-CH2-C6H5

              ||

              O

This shows the acetamide functional group (C=O and NH2) bonded to a CH2 group, which in turn is bonded to a phenyl ring (C6H5).

 

2-phenylacetamide Uses

2-Phenylacetamide CAS 103-81-1 is used in various applications, primarily in the fields of chemistry, pharmacology, and industrial processes. Here are some of its uses:

1. Pharmaceutical Intermediates

Synthesis of drugs: 2-Phenylacetamide serves as an important intermediate in the synthesis of various pharmaceutical compounds. It is used in the production of analgesics (pain relievers) and antipyretics (fever reducers).

2. Precursor in the Synthesis of Other Chemicals

It is involved in the production of more complex molecules that are useful in different chemical reactions. Its structure makes it a versatile building block in the synthesis of various organic compounds.

3. Fragrance Industry

Flavor and fragrance additives: Due to its aromatic nature, 2-phenylacetamide can be used as a precursor or intermediate in the production of substances used in perfumes, flavors, and fragrances, giving certain products floral, sweet, or fruity scents.

4. Pesticide and Agrochemical Development

In some cases, 2-phenylacetamide may be part of the synthesis of agrochemicals, especially those used for controlling pests or fungi, though this is a more specialized and less common application.

5. Polymer Chemistry

It may be used as a monomer or in the formulation of specialized polymers or materials, although this is a less widespread application compared to other uses.

6. Research and Development

Chemical research: 2-phenylacetamide is also used in research settings, particularly in organic chemistry and materials science, to investigate reactions, mechanisms, or properties related to amides and aromatic compounds.

7. Medical and Toxicological Studies

Toxicology studies: It is sometimes used in toxicological testing to study the biological effects of amide-containing compounds and their breakdown products in organisms.

8. Cosmetic Formulations

2-phenylacetamide CAS 103-81-1 can sometimes be found in cosmetic formulations, especially in skin-care or hair-care products, where it might be included as part of a broader fragrance profile.

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